Two sample MR report
NME5_T Proliferating against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | -0.0203320 | 0.2805434 | 0.9488206 |
| Weighted median | 4 | 0.0171862 | 0.0088647 | 0.0525338 |
| Inverse variance weighted | 4 | 0.0173177 | 0.0077508 | 0.0254621 |
| Simple mode | 4 | 0.0164060 | 0.0115842 | 0.2516798 |
| Weighted mode | 4 | 0.0163914 | 0.0109882 | 0.2325791 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0018640 | 2 | 0.9990684 |
| Inverse variance weighted | 0.0198881 | 3 | 0.9992585 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0564696 | 0.4206184 | 0.9054931 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 4.48e-05 | 0 | TRUE | 0.5251375 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
